Plekha8 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8

GeneMGI:2681164Synonyms: FAPP2

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Growth/size/body region Renal/urinary system

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	1 supporting dataset	Plekha8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Plekha8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Plekha8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
polycystic kidney	1 supporting dataset	Plekha8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plekha8.

Associated images

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Histopathology

There is no histopathology data found for Plekha8.

IMPC related publications

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External links

No external links available for Plekha8.

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*Plekha8^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Plekha8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Plekha8^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Plekha8^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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