Satb2 | special AT-rich sequence binding protein 2

GeneMGI:2679336Synonyms: BAP002

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Vision/eye Hematopoietic system Mortality/aging Craniofacial

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

4Associated diseases

Expression examined in:42Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



increased circulating alkaline phosphatase level	1 supporting dataset	Satb2^em3(IMPC)Tcp	heterozygote	Early adult	2.65x10^-10
enlarged lymph nodes	2 supporting datasets	Satb2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Satb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Satb2^em3(IMPC)Tcp	heterozygote	Early adult	3.84x10^-9
abnormal craniofacial morphology	1 supporting dataset	Satb2^em3(IMPC)Tcp	homozygote	E15.5	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Satb2^em3(IMPC)Tcp	heterozygote	Early adult	2.23x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Satb2^em3(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Satb2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Satb2.

Associated images

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Histopathology

There is no histopathology data found for Satb2.

IMPC related publications

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External links

No external links available for Satb2.

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*Satb2^em2(IMPC)Mbp*	Indel	‌	mouse
*Satb2^em3(IMPC)Tcp*	Indel	‌	mouse
*Satb2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Satb2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Satb2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Satb2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Satb2^{tm41799(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Satb2^{tm41799(L1L2_gt1_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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