Zfp760 | zinc finger protein 760

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating calcium level1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult2.3x10-5 
increased hemoglobin content1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult7.37x10-6 
increased circulating serum albumin level1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult3.61x10-8 
increased erythrocyte cell number1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult1.39x10-6 
increased circulating alkaline phosphatase level1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult1.67x10-7 
increased hematocrit1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult3.27x10-6 
thrombocytopenia1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult1.43x10-5 
increased circulating total protein level1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult5.44x10-5 
decreased IgE level1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult1.24x10-5 
decreased body weight1 supporting datasetZfp760tm1a(EUCOMM)HmguheterozygoteEarly adult5.62x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp760tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Zfp760tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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