Hmcn2 | hemicentin 2

GeneMGI:2677838

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Cardiovascular system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased hematocrit	1 supporting dataset	Hmcn2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.72x10^-8
abnormal heart left ventricle morphology	2 supporting datasets	Hmcn2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.13x10^-5
increased hemoglobin content	1 supporting dataset	Hmcn2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.27x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hmcn2.

Associated images

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Histopathology

There is no histopathology data found for Hmcn2.

IMPC related publications

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External links

No external links available for Hmcn2.

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*Hmcn2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hmcn2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hmcn2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Hmcn2^{tm33638(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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