Dolk | dolichol kinase

GeneMGI:2677836Synonyms: Tmem15

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetDolkem1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetDolkem1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dolkem1(IMPC)JIndelmouse
Dolktm444645(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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