Dagla | diacylglycerol lipase, alpha

GeneMGI:2677061Synonyms: Nsddr

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Nervous system Respiratory system Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased thigmotaxis	2 supporting datasets	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.8x10^-5
increased startle reflex	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.27x10^-6
small heart	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased brain size	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
small lung	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.9x10^-5
small liver	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
small stomach	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
small thymus	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Dagla^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Dagla.

Associated images

Loading...

Histopathology

There is no histopathology data found for Dagla.

IMPC related publications

Loading...

External links

No external links available for Dagla.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Dagla^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Dagla^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dagla^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Dagla^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dagla^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Dagla^{tm40176(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes