Focad | focadhesin
Physiological systems
21 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological Craniofacial Mortality/aging
12 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, incomplete penetrance | 3 supporting datasets | Focadem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
abnormal facial morphology | 2 supporting datasets | Focadem1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
abnormal placenta size | 1 supporting dataset | Focadem1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
cleft palate | 1 supporting dataset | Focadem1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
anophthalmia | 1 supporting dataset | Focadem1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
increased exploration in new environment | 1 supporting dataset | Focadem1(IMPC)Bay | heterozygote | Late adult | 1.13x10-8 | ||
decreased spleen weight | 1 supporting dataset | Focadem1(IMPC)Bay | heterozygote | Late adult | 7.14x10-5 |
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Focadem1(IMPC)Bay | Exon Deletion | | mouse |
Focadtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Focadtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |