Focad | focadhesin

GeneMGI:2676921Synonyms: BC057079

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Immune system Embryo Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological Craniofacial Mortality/aging

12 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsFocadem1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal facial morphology2 supporting datasetsFocadem1(IMPC)BayhomozygoteE18.5N/A * 
abnormal placenta size1 supporting datasetFocadem1(IMPC)BayhomozygoteE18.5N/A * 
cleft palate1 supporting datasetFocadem1(IMPC)BayhomozygoteE18.5N/A * 
anophthalmia1 supporting datasetFocadem1(IMPC)BayhomozygoteE18.5N/A * 
increased exploration in new environment1 supporting datasetFocadem1(IMPC)BayheterozygoteLate adult1.13x10-8 
decreased spleen weight1 supporting datasetFocadem1(IMPC)BayheterozygoteLate adult7.14x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Focadem1(IMPC)BayExon Deletionmouse
Focadtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Focadtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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