Akap13 | A kinase anchor protein 13

GeneMGI:2676556Synonyms: 1700026G02Rik, 5830460E08Rik, +5 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Vision/eye Liver/biliary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
microphthalmia1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
improved glucose tolerance1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adult3.75x10-5 
small liver1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetAkap13em1(IMPC)MbphomozygoteEarly adult1.41x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Akap13em1(IMPC)MbpExon Deletionmouse

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