Abca12 | ATP-binding cassette, sub-family A member 12

GeneMGI:2676312Synonyms: 4833417A11Rik, 4832428G11Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Hearing/vestibular/ear Craniofacial Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal outer ear morphology1 supporting datasetAbca12em1(IMPC)JhomozygoteE18.5N/A * 
abnormal facial morphology1 supporting datasetAbca12em1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetAbca12em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal skin appearance1 supporting datasetAbca12em1(IMPC)JhomozygoteE18.5N/A * 
edema1 supporting datasetAbca12em1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Abca12em1(IMPC)JExon Deletionmouse
Abca12tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Abca12tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Abca12tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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