Trpm6 | transient receptor potential cation channel, subfamily M, member 6
Physiological systems
16 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological
11 No significant impact
8 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased circulating phosphate level | 1 supporting dataset | Trpm6tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.71x10-5 | ||
decreased mean corpuscular volume | 1 supporting dataset | Trpm6tm1b(KOMP)Wtsi | heterozygote | Early adult | 9.67x10-6 | ||
increased grip strength | 2 supporting datasets | Trpm6tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.65x10-6 | ||
abnormal eye anterior chamber depth | 1 supporting dataset | Trpm6tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.89x10-5 | ||
increased body length | 1 supporting dataset | Trpm6tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.62x10-7 |
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External links
No external links available for Trpm6.
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Trpm6tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Trpm6tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Trpm6tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Trpm6tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |