Arhgap33 | Rho GTPase activating protein 33

GeneMGI:2673998Synonyms: NOMA-GAP, Tcgap, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Behavior/neurological Cardiovascular system Mortality/aging

18 No significant impact

3 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues

Phenotypes

decreased heart weight1 supporting datasetArhgap33tm1b(KOMP)WtsiheterozygoteEarly adult8.89x10-5 
preweaning lethality, incomplete penetrance3 supporting datasetsArhgap33tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetArhgap33tm1b(KOMP)WtsihomozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetArhgap33tm1b(KOMP)WtsiheterozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arhgap33tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Arhgap33tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Arhgap33tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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