Tnfsf18 | tumor necrosis factor (ligand) superfamily, member 18

GeneMGI:2673064Synonyms: Gitrl, GITR ligand

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Growth/size/body region Hematopoietic system

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

decreased lean body mass1 supporting datasetTnfsf18tm1.1(KOMP)VlcghomozygoteEarly adult5.56x10-5 
increased hematocrit1 supporting datasetTnfsf18tm1.1(KOMP)VlcghomozygoteEarly adult2.41x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tnfsf18tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Tnfsf18tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Tnfsf18tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tnfsf18tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Tnfsf18tm45212(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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