Arhgef17 | Rho guanine nucleotide exchange factor 17

GeneMGI:2673002

Physiological systems

12 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Mortality/aging Cardiovascular system Renal/urinary system

8 No significant impact

12 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



thick ventricular wall	1 supporting dataset	Arhgef17^em1(IMPC)Bay	homozygote	Early adult	3.96x10^-5
enlarged kidney	1 supporting dataset	Arhgef17^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Arhgef17^em1(IMPC)Bay	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arhgef17.

Associated images

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Histopathology

There is no histopathology data found for Arhgef17.

IMPC related publications

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External links

No external links available for Arhgef17.

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*Arhgef17^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Arhgef17^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Arhgef17^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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