Col27a1 | collagen, type XXVII, alpha 1

GeneMGI:2672118Synonyms: 5730512J02Rik

Physiological systems

22 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Growth/size/body region Digestive/alimentary Vision/eye Liver/biliary system Hematopoietic system Skeleton Craniofacial Mortality/aging Cardiovascular system Renal/urinary system

9 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta vasculature	1 supporting dataset	Col27a1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Col27a1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
pale liver	1 supporting dataset	Col27a1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
increased bone mineral density	1 supporting dataset	Col27a1^em1(IMPC)Mbp	heterozygote	Early adult	8.44x10^-6
cleft palate	1 supporting dataset	Col27a1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Col27a1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Col27a1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Col27a1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Col27a1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal retina morphology	1 supporting dataset	Col27a1^em1(IMPC)Mbp	heterozygote	Early adult	6.2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Col27a1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Col27a1.

IMPC related publications

Loading...

External links

No external links available for Col27a1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Col27a1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Col27a1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Col27a1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Col27a1^{tm36205(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Col27a1^{tm36205(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes