Shank2 | SH3 and multiple ankyrin repeat domains 2

GeneMGI:2671987Synonyms: ProSAP1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Hematopoietic system Behavior/neurological Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



hyperactivity	9 supporting datasets	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	6.2x10^-32
increased thigmotaxis	2 supporting datasets	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	3.04x10^-6
abnormal behavior	1 supporting dataset	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	3.04x10^-6
increased bone mineral content	2 supporting datasets	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	2.42x10^-6
decreased erythrocyte cell number	1 supporting dataset	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	3.96x10^-6
limb grasping	1 supporting dataset	Shank2^{em2(IMPC)Rbrc}	homozygote	Early adult	2.52x10^-6
limb grasping	1 supporting dataset	Shank2^{em2(IMPC)Rbrc}	homozygote	Late adult	6.75x10^-9
abnormal locomotor behavior	1 supporting dataset	Shank2^{em2(IMPC)Rbrc}	homozygote	Late adult	1.98x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Shank2.

Associated images

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Histopathology

There is no histopathology data found for Shank2.

IMPC related publications

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External links

No external links available for Shank2.

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*Shank2^{em1(IMPC)Rbrc}*	Indel	‌	mouse
*Shank2^{em2(IMPC)Rbrc}*	Exon Deletion	‌	mouse

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