Nrde2 | nrde-2 necessary for RNA interference, domain containing

GeneMGI:2670969Synonyms: 6720454P05Rik, BC002230

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased bone mineral content	1 supporting dataset	Nrde2^{tm2a(KOMP)Wtsi}	heterozygote	Early adult	2.07x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Nrde2^{tm2a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Nrde2^{tm2a(KOMP)Wtsi}	heterozygote	Early adult	9.7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nrde2.

Associated images

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Histopathology

There is no histopathology data found for Nrde2.

IMPC related publications

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External links

No external links available for Nrde2.

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*Nrde2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Nrde2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nrde2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nrde2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nrde2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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