Med13l | mediator complex subunit 13-like

GeneMGI:2670178Synonyms: 2210413I17Rik, 9030618F05Rik, +3 more

Physiological systems

14 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Craniofacial Cardiovascular system

8 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal craniofacial morphology1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal facial morphology1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
edema1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal blood vessel morphology1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
microphthalmia1 supporting datasetMed13lem1(IMPC)MbphomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Med13lem1(IMPC)MbpInter-exon deletionmouse
Med13ltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Med13ltm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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