Rtn4rl2 | reticulon 4 receptor-like 2

GeneMGI:2669796Synonyms: Ngrl3, Ngrh1, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Growth/size/body region Nervous system Hearing/vestibular/ear Vision/eye Hematopoietic system Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
abnormal auditory brainstem response	4 supporting datasets	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	1.83x10^-6
small testis	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	1.57x10^-6
decreased brain size	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal brain morphology	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Rtn4rl2^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rtn4rl2.

Associated images

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Histopathology

There is no histopathology data found for Rtn4rl2.

IMPC related publications

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External links

No external links available for Rtn4rl2.

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*Rtn4rl2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rtn4rl2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rtn4rl2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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