Myo18a | myosin XVIIIA

GeneMGI:2667185Synonyms: MyoPDZ

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Limbs/digits/tail Liver/biliary system Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
pale yolk sac1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsMyo18atm1b(KOMP)WtsihomozygoteEarly adultN/A * 
pale liver1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
abnormal placenta size1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
abnormal limb bud morphology1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
pallor1 supporting datasetMyo18atm1b(KOMP)WtsihomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Myo18atm119203(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Myo18atm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Myo18atm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Myo18atm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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