Irgq | immunity-related GTPase family, Q

GeneMGI:2667176Synonyms: FKSG27

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased heart rate1 supporting datasetIrgqem1(IMPC)JhomozygoteEarly adult5.48x10-6 
prolonged RR interval1 supporting datasetIrgqem1(IMPC)JhomozygoteEarly adult6.55x10-8 
decreased circulating bilirubin level1 supporting datasetIrgqem1(IMPC)JhomozygoteEarly adult1.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Irgqem1(IMPC)JExon Deletionmouse
Irgqtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Irgqtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Irgqtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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