P2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2

GeneMGI:2665170Synonyms: P2x2, P2X2a

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased locomotor activity	2 supporting datasets	P2rx2^em1(IMPC)H	homozygote	Early adult	2.56x10^-5
decreased circulating glucose level	1 supporting dataset	P2rx2^em1(IMPC)H	homozygote	Early adult	5.25x10^-5
small testis	1 supporting dataset	P2rx2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	P2rx2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.15x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for P2rx2.

Associated images

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Histopathology

There is no histopathology data found for P2rx2.

IMPC related publications

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External links

No external links available for P2rx2.

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*P2rx2^em1(IMPC)H*	Exon Deletion	‌	mouse
*P2rx2^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*P2rx2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*P2rx2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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