Dsg1b | desmoglein 1 beta

GeneMGI:2664357Synonyms: Dsg5

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Vision/eye Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eyelid morphology	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.97x10^-13
thrombocytopenia	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.29x10^-5
abnormal coat appearance	2 supporting datasets	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.06x10^-6
abnormal iris morphology	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.78x10^-5
abnormal lens morphology	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.38x10^-5
increased bone mineral content	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.68x10^-5
abnormal cornea morphology	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.22x10^-8
cataract	1 supporting dataset	Dsg1b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Dsg1b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Dsg1b.

IMPC related publications

Loading...

External links

No external links available for Dsg1b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Dsg1b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dsg1b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes