Plac9 | placenta specific 9

GeneMGI:2663998Synonyms: Plac9b, Gm9780, +3 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

12 No significant impact

6 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating fructosamine level1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult6.28x10-5 
decreased fasting circulating glucose level1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult3.62x10-6 
decreased lean body mass1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult8.51x10-7 
decreased bone mineral content2 supporting datasetsPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult2.68x10-5 
decreased mean corpuscular volume1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult2.27x10-5 
increased total body fat amount2 supporting datasetsPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult4.4x10-12 
decreased red blood cell distribution width1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult5.49x10-6 
decreased neutrophil cell number1 supporting datasetPlac9tm1b(EUCOMM)HmguhomozygoteEarly adult1.64x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Plac9tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Plac9tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Plac9tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Plac9tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Plac9tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Plac9tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Plac9tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Plac9tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Plac9tm80657(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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