Mogat2 | monoacylglycerol O-acyltransferase 2

GeneMGI:2663253Synonyms: Mgat2, DGAT2L5

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Integument Nervous system Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal testis morphology1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased prepulse inhibition3 supporting datasetsMogat2em1(IMPC)MbphomozygoteEarly adult8.42x10-6 
abnormal seminal vesicle morphology1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased locomotor activity1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adult4.29x10-7 
small seminal vesicle1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetMogat2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mogat2em1(IMPC)MbpExon Deletionmouse
Mogat2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mogat2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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