Prss33 | serine protease 33

GeneMGI:2661234Synonyms: tryptase-6, Eos, +1 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal thymus morphology	2 supporting datasets	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased body weight	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.67x10^-5
enlarged spleen	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased prepulse inhibition	2 supporting datasets	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.92x10^-5
enlarged uterus	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Prss33^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss33.

Associated images

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Histopathology

There is no histopathology data found for Prss33.

IMPC related publications

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External links

No external links available for Prss33.

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*Prss33^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse
*Prss33^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Prss33^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prss33^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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