Cnksr2 | connector enhancer of kinase suppressor of Ras 2

GeneMGI:2661175Synonyms: Cnk2, Ksr2

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetCnksr2em1(IMPC)JhomozygoteEarly adult1.98x10-7 
abnormal bone structure1 supporting datasetCnksr2em1(IMPC)JhomozygoteEarly adult7.23x10-6 
impaired glucose tolerance1 supporting datasetCnksr2em1(IMPC)JhomozygoteEarly adult8.97x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cnksr2em1(IMPC)JExon Deletionmouse
Cnksr2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Cnksr2tm300368(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cnksr2tm41070(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cnksr2tm41070(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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