Phactr1 | phosphatase and actin regulator 1

GeneMGI:2659021Synonyms: 9630030F18Rik, Rpel1

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system Skeleton Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal eye morphology	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
decreased leukocyte cell number	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	3.89x10^-6
increased bone mineral content	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Early adult	3.3x10^-8
enlarged lymph nodes	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Middle aged adult	2.95x10^-7
decreased circulating aspartate transaminase level	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	1.07x10^-24
enlarged spleen	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
decreased circulating alanine transaminase level	1 supporting dataset	Phactr1^em1(IMPC)Mbp	homozygote	Late adult	2.77x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Phactr1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Phactr1.

IMPC related publications

Loading...

External links

No external links available for Phactr1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Phactr1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Phactr1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Phactr1^{tm44835(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes