Gmeb2 | glucocorticoid modulatory element binding protein 2

GeneMGI:2652836

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased lean body mass	1 supporting dataset	Gmeb2^em1(IMPC)J	heterozygote	Early adult	7.71x10^-5
decreased circulating aspartate transaminase level	1 supporting dataset	Gmeb2^em1(IMPC)J	heterozygote	Early adult	9.41x10^-14
decreased circulating bilirubin level	1 supporting dataset	Gmeb2^em1(IMPC)J	heterozygote	Early adult	8.4x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Gmeb2^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased startle reflex	1 supporting dataset	Gmeb2^em1(IMPC)J	heterozygote	Early adult	1.54x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gmeb2.

Associated images

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Histopathology

There is no histopathology data found for Gmeb2.

IMPC related publications

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External links

No external links available for Gmeb2.

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*Gmeb2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Gmeb2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Gmeb2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gmeb2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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