Lcorl | ligand dependent nuclear receptor corepressor-like
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Hearing/vestibular/ear Behavior/neurological Cardiovascular system Mortality/aging
13 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased heart rate | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | 1.65x10-5 | ||
abnormal auditory brainstem response | 4 supporting datasets | Lcorlem1(IMPC)J | homozygote | Early adult | 1.85x10-9 | ||
prolonged RR interval | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | 5.14x10-10 | ||
increased aggression | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | 6.1x10-5 | ||
hyperactivity | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | 7.27x10-5 | ||
increased exploration in new environment | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | 8.83x10-5 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Lcorlem1(IMPC)J | homozygote | Early adult | N/A * |
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External links
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Lcorlem1(IMPC)J | Exon Deletion | | mouse |