Noxa1 | NADPH oxidase activator 1

GeneMGI:2449980

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	1 supporting dataset	Noxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Noxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.47x10^-6
decreased grip strength	1 supporting dataset	Noxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.89x10^-5
abnormal vocalization	1 supporting dataset	Noxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.66x10^-6
abnormal thymus morphology	1 supporting dataset	Noxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Noxa1.

Associated images

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Histopathology

There is no histopathology data found for Noxa1.

IMPC related publications

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External links

No external links available for Noxa1.

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*Noxa1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Noxa1^{tm40202(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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