Map3k9 | mitogen-activated protein kinase kinase kinase 9

GeneMGI:2449952Synonyms: Mlk1

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased neutrophil cell number	1 supporting dataset	Map3k9^em1(IMPC)Mbp	homozygote	Early adult	2.79x10^-5
small kidney	1 supporting dataset	Map3k9^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Map3k9^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
eye hemorrhage	1 supporting dataset	Map3k9^em1(IMPC)Mbp	homozygote	Early adult	2.93x10^-5
abnormal skin morphology	1 supporting dataset	Map3k9^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Map3k9^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Map3k9^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Map3k9.

Associated images

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Histopathology

There is no histopathology data found for Map3k9.

IMPC related publications

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External links

No external links available for Map3k9.

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*Map3k9^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Map3k9^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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