Afmid | arylformamidase

GeneMGI:2448704Synonyms: Kf, formylkynureninase, +3 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:

Life Stage:



hyperactivity	1 supporting dataset	Afmid^em1Llp	homozygote	Late adult	6.15x10^-5
increased mean corpuscular volume	1 supporting dataset	Afmid^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.21x10^-7
increased circulating glucose level	1 supporting dataset	Afmid^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.66x10^-5
decreased grip strength	2 supporting datasets	Afmid^em1Llp	homozygote	Early adult	3.4x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Afmid^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.27x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Afmid.

Associated images

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Histopathology

There is no histopathology data found for Afmid.

IMPC related publications

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External links

No external links available for Afmid.

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*Afmid^em1Llp*	Intra-exon deletion	‌	mouse
*Afmid^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Afmid^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Afmid^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Afmid^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Afmid^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Afmid^{tm47423(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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