Myo3b | myosin IIIB

GeneMGI:2448580Synonyms: A430065P19Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

convulsive seizures1 supporting datasetMyo3btm1b(EUCOMM)HmguhomozygoteEarly adult2.99x10-5 
abnormal bone structure1 supporting datasetMyo3btm1b(EUCOMM)HmguhomozygoteEarly adult2x10-5 
increased heart weight1 supporting datasetMyo3btm1b(EUCOMM)HmguhomozygoteEarly adult6.52x10-5 
decreased leukocyte cell number1 supporting datasetMyo3btm1b(EUCOMM)HmguhomozygoteEarly adult1.38x10-5 
increased bone mineral content1 supporting datasetMyo3btm1b(EUCOMM)HmguhomozygoteEarly adult1.82x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Myo3btm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Myo3btm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Myo3btm39337(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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