Ythdc2 | YTH domain containing 2
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Adipose tissue Growth/size/body region Skeleton Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased total body fat amount | 2 supporting datasets | Ythdc2em1(IMPC)Bay | homozygote | Early adult | 8.49x10-19 | ||
| male infertility | 1 supporting dataset | Ythdc2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| female infertility | 1 supporting dataset | Ythdc2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| decreased bone mineral content | 2 supporting datasets | Ythdc2em1(IMPC)Bay | homozygote | Early adult | 5.34x10-21 | ||
| decreased heart weight | 1 supporting dataset | Ythdc2em1(IMPC)Bay | homozygote | Early adult | 3.23x10-5 | ||
| decreased lean body mass | 2 supporting datasets | Ythdc2em1(IMPC)Bay | homozygote | Early adult | 4.15x10-17 | ||
| decreased bone mineral density | 1 supporting dataset | Ythdc2em1(IMPC)Bay | homozygote | Early adult | 1.98x10-16 |
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External links
No external links available for Ythdc2.
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| Ythdc2em1(IMPC)Bay | Exon Deletion | | mouse |
| Ythdc2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ythdc2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |