Cox18 | cytochrome c oxidase assembly protein 18

GeneMGI:2448532

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Cox18^em1(IMPC)J	homozygote	E9.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Cox18^em1(IMPC)J	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Cox18^em1(IMPC)J	homozygote	E12.5	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Cox18^em1(IMPC)J	heterozygote	Early adult	4.07x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Cox18^em1(IMPC)J	homozygote	Early adult	N/A ^*
prenatal lethality	1 supporting dataset	Cox18^em1(IMPC)J	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cox18.

Associated images

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Histopathology

There is no histopathology data found for Cox18.

IMPC related publications

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External links

No external links available for Cox18.

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*Cox18^em1(IMPC)J*	Exon Deletion	‌	mouse
*Cox18^{tm45902(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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