Fbxl16 | F-box and leucine-rich repeat protein 16

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues

Phenotypes

unresponsive to tactile stimuli1 supporting datasetFbxl16tm1b(KOMP)WtsihomozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetFbxl16tm1b(KOMP)WtsiheterozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsFbxl16tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxl16tm119151(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Fbxl16tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fbxl16tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Fbxl16tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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