Mgst2 | microsomal glutathione S-transferase 2

GeneMGI:2448481Synonyms: MGST-II, GST2

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Integument Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small kidney1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged cecum1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal cecum morphology1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adult5.01x10-10 
abnormal spleen morphology1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetMgst2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mgst2em1(IMPC)MbpExon Deletionmouse
Mgst2tm212190(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector
Mgst2tm88126(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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