Fancd2 | Fanconi anemia, complementation group D2

GeneMGI:2448480Synonyms: 2410150O07Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system Mortality/aging Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating iron level	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.08x10^-5
decreased locomotor activity	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.49x10^-5
small kidney	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	heterozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.17x10^-6
abnormal retina blood vessel morphology	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	heterozygote	Early adult	9.87x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Fancd2^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fancd2.

Associated images

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Histopathology

There is no histopathology data found for Fancd2.

IMPC related publications

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External links

No external links available for Fancd2.

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*Fancd2^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Fancd2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Fancd2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fancd2^{tm43555(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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