H4c1 | H4 clustered histone 1

GeneMGI:2448419Synonyms: Hist1h4a

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Integument Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal eye morphology	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.05x10^-7
abnormal freezing behavior	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.04x10^-5
abnormal retina vasculature morphology	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.08x10^-7
abnormal skin morphology	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	H4c1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H4c1.

Associated images

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Histopathology

There is no histopathology data found for H4c1.

IMPC related publications

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External links

No external links available for H4c1.

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*H4c1^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse

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