Serac1 | serine active site containing 1

GeneMGI:2447813Synonyms: 4930511N22Rik, D17Ertd141e

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased freezing behavior	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	1.84x10^-6
decreased exploration in new environment	2 supporting datasets	Serac1^em1(IMPC)Tcp	homozygote	Early adult	3.18x10^-10
decreased locomotor activity	4 supporting datasets	Serac1^em1(IMPC)Tcp	homozygote	Early adult	7.09x10^-6
abnormal freezing behavior	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	5.15x10^-5
decreased vertical activity	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	4.67x10^-6
enlarged lymph nodes	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enhanced contextual conditioning behavior	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	6.63x10^-5
abnormal ovary morphology	1 supporting dataset	Serac1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serac1.

Associated images

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Histopathology

There is no histopathology data found for Serac1.

IMPC related publications

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External links

No external links available for Serac1.

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*Serac1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Serac1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Serac1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Serac1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Serac1^{tm42544(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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