Klk15 | kallikrein related-peptidase 15

GeneMGI:2447533

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Nervous system Behavior/neurological Skeleton Craniofacial

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	2 supporting datasets	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.08x10^-5
decreased prepulse inhibition	4 supporting datasets	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.84x10^-6
abnormal cranium morphology	1 supporting dataset	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.55x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.78x10^-5
abnormal joint morphology	1 supporting dataset	Klk15^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.43x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klk15.

Associated images

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Histopathology

There is no histopathology data found for Klk15.

IMPC related publications

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External links

No external links available for Klk15.

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*Klk15^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Klk15^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Klk15^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Klk15^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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