Smg5 | SMG5 nonsense mediated mRNA decay factor
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Nervous system Mortality/aging Cardiovascular system
18 No significant impact
2 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Smg5em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| hemorrhage | 1 supporting dataset | Smg5em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| spina bifida | 1 supporting dataset | Smg5em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Smg5em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Smg5em1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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External links
No external links available for Smg5.
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| Smg5em1(IMPC)Mbp | Exon Deletion | | mouse |
| Smg5tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Smg5tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |