Tenm4 | teneurin transmembrane protein 4

GeneMGI:2447063Synonyms: ELM2, Ten-m4, +4 more

Physiological systems

19 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

8 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased thigmotaxis	2 supporting datasets	Tenm4^em1(IMPC)Tcp	homozygote	Early adult	6.56x10^-5
decreased lean body mass	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	8.54x10^-6
cornea opacity	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	1.24x10^-7
increased circulating sodium level	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	1.97x10^-6
enlarged urinary bladder	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
increased circulating chloride level	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	6.24x10^-6
increased bone mineral content	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	8.2x10^-6
increased grip strength	2 supporting datasets	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	1.01x10^-6
anophthalmia	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased spleen weight	1 supporting dataset	Tenm4^em1(IMPC)Tcp	homozygote	Late adult	9.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tenm4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tenm4.

IMPC related publications

Loading...

External links

No external links available for Tenm4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tenm4^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Tenm4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tenm4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tenm4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tenm4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes