Kif18b | kinesin family member 18B

GeneMGI:2446979Synonyms: 3000004C01Rik, N-8 kinesin

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetKif18btm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased circulating triglyceride level1 supporting datasetKif18btm1a(EUCOMM)WtsiheterozygoteEarly adult4.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kif18btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Kif18btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Kif18btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Kif18btm43221(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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