Frmpd1 | FERM and PDZ domain containing 1

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Limbs/digits/tail Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal autopod morphology1 supporting datasetFrmpd1em1(IMPC)JhomozygoteLate adult1.29x10-5 
decreased bone mineral density1 supporting datasetFrmpd1em1(IMPC)BayhomozygoteEarly adult8.3x10-5 
abnormal hindlimb morphology1 supporting datasetFrmpd1em1(IMPC)JhomozygoteLate adult9.79x10-5 
decreased grip strength2 supporting datasetsFrmpd1em1(IMPC)JhomozygoteEarly adult7.87x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Frmpd1em1(IMPC)BayInsertionmouse
Frmpd1em1(IMPC)JExon Deletionmouse
Frmpd1tm39117(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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