Edc4 | enhancer of mRNA decapping 4

GeneMGI:2446249

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased erythrocyte cell number	1 supporting dataset	Edc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.39x10^-5
increased grip strength	2 supporting datasets	Edc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.92x10^-12
preweaning lethality, complete penetrance	1 supporting dataset	Edc4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Edc4.

Associated images

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Histopathology

There is no histopathology data found for Edc4.

IMPC related publications

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External links

No external links available for Edc4.

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*Edc4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Edc4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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