Galnt18 | polypeptide N-acetylgalactosaminyltransferase 18

GeneMGI:2446239Synonyms: 2900011G21Rik, Galntl4

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system

13 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased circulating fructosamine level1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adult7.66x10-6 
increased lean body mass1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adult2.76x10-5 
decreased total body fat amount1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adult5.87x10-5 
increased circulating alkaline phosphatase level1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adult3.65x10-7 
increased red blood cell distribution width1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adult2.37x10-8 
increased NK cell number1 supporting datasetGalnt18tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Galnt18tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Galnt18tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Galnt18tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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