Arhgef16 | Rho guanine nucleotide exchange factor 16

GeneMGI:2446219Synonyms: Neuroblastoma

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content1 supporting datasetArhgef16em1(IMPC)MbphomozygoteEarly adult4.8x10-5 
enlarged kidney1 supporting datasetArhgef16em1(IMPC)MbphomozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetArhgef16em1(IMPC)MbphomozygoteEarly adult8.52x10-12 
abnormal kidney morphology1 supporting datasetArhgef16em1(IMPC)MbphomozygoteEarly adultN/A * 
increased monocyte cell number1 supporting datasetArhgef16em1(IMPC)MbphomozygoteEarly adult5.38x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Arhgef16em1(IMPC)MbpExon Deletionmouse

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