Lpgat1 | lysophosphatidylglycerol acyltransferase 1
GeneMGI:2446186
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Pigmentation Integument Vision/eye Behavior/neurological Skeleton Cardiovascular system Mortality/aging
12 No significant impact
5 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal retina blood vessel morphology | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Early adult | 4.5x10-7 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased anxiety-related response | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Early adult | 5.19x10-6 | ||
| decreased bone mineral content | 2 supporting datasets | Lpgat1em1(IMPC)J | heterozygote | Early adult | 4.55x10-6 | ||
| limb grasping | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Late adult | 1.5x10-7 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Late adult | 1.02x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Early adult | 9.35x10-5 | ||
| impaired righting response | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Late adult | 1.03x10-6 | ||
| increased vertical activity | 1 supporting dataset | Lpgat1em1(IMPC)J | homozygote | Early adult | 1.71x10-6 |
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External links
No external links available for Lpgat1.
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| Lpgat1em1(IMPC)J | Exon Deletion | | mouse |
| Lpgat1tm49405(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |