Marveld2 | MARVEL (membrane-associating) domain containing 2

GeneMGI:2446166Synonyms: Tric, Mrvldc2, +4 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Hearing/vestibular/ear Nervous system Behavior/neurological Cardiovascular system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.01x10^-6
abnormal auditory brainstem response	5 supporting datasets	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.63x10^-7
abnormal startle reflex	1 supporting dataset	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.55x10^-17
decreased prepulse inhibition	7 supporting datasets	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.44x10^-31
abnormal ear morphology	1 supporting dataset	Marveld2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.18x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Marveld2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Marveld2.

IMPC related publications

Loading...

External links

No external links available for Marveld2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Marveld2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Marveld2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Marveld2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes